SCHEMBL11248165

SCHEMBL11248165

CCO[Si](CN)(CCc1ccccc1)OCC

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
HTR2A P28223 2/20 0.42
LOXL2 Q9Y4K0 2/20 0.42
CYP2A6 P11509 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ALDH1A1 P00352 1/20 0.40
MAOA P21397 2/20 0.38
AOC3 Q16853 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
IDO1 P14902 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
TP53 P04637 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716563 0.89 TDP1 (0.43) SMN1; SMN2HTR2ALOXL2CYP2A6TAAR1
SCHEMBL27904372 0.86 MAOA (0.48) SMN1; SMN2HTR2ALOXL2CYP2A6TAAR1
SCHEMBL4082752 0.82 TDP1 (0.42) SMN1; SMN2TAAR1ALDH1A1TDP1TP53
SCHEMBL4079136 0.82 ALDH1A1 (0.43) SMN1; SMN2TAAR1ALDH1A1AOC3TDP1
SCHEMBL4077455 0.82 TDP1 (0.38) SMN1; SMN2TAAR1ALDH1A1AOC3TDP1
SCHEMBL17750059 0.77 TDP1 (0.43) SMN1; SMN2HTR2ALOXL2CYP2A6TAAR1
SCHEMBL107467 0.77 TDP1 (0.43) SMN1; SMN2HTR2ALOXL2CYP2A6TAAR1
SCHEMBL104845 0.76 TDP1 (0.41) SMN1; SMN2HTR2ALOXL2CYP2A6TAAR1
SCHEMBL2872464 0.76 TDP1 (0.41) SMN1; SMN2HTR2ALOXL2CYP2A6TAAR1
SCHEMBL8430151 0.75 TAAR1 (0.38) SMN1; SMN2HTR2ALOXL2CYP2A6TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4336395-A PROCESS FOR PREPARING (AMINOMETHYL) PHENYL-ETHYLDIMETHYLMETHOXYSILANE PETRARCH SYSTEMS, INC. (US) 1982-06-22 US claimed
US-4336395-A PROCESS FOR PREPARING (AMINOMETHYL) PHENYL-ETHYLDIMETHYLMETHOXYSILANE PETRARCH SYSTEMS, INC. (US) 1982-06-22 US disclosed