Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249308 | 0.88 | POLB (0.41) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL11236106 | 0.79 | LMNA (0.41) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL11241152 | 0.78 | ALDH1A1 (0.38) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11243909 | 0.76 | USP2 (0.35) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL11240689 | 0.73 | ALDH1A1 (0.37) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11248698 | 0.73 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL11235754 | 0.73 | MEN1 (0.40) | OPRM1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL11246583 | 0.72 | HSD17B10 (0.36) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL11243202 | 0.72 | HSD17B10 (0.36) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL11237613 | 0.70 | POLB (0.35) | GAAALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | claimed |