Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.80 |
| ▸ | THRB | P10828 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 5/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20435795 | 0.86 | RAD52 (0.64) | MAPTTHRBGAATP53SMN1; SMN2 | |
| SCHEMBL20435788 | 0.85 | MAPT (0.68) | MAPTTHRBGAATP53SMN1; SMN2 | |
| SCHEMBL32659740 | 0.84 | MAPT (0.70) | MAPTTHRBGAATP53PDE4B | |
| SCHEMBL11244977 | 0.80 | ALDH1A1 (0.78) | MAPTGAATP53PDE4BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11248141 | 0.80 | MAPT (0.65) | MAPTGAATP53PDE4BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11254237 | 0.79 | ALDH1A1 (0.80) | MAPTGAATP53PDE4BSMN1; SMN2 | |
| SCHEMBL11229286 | 0.79 | MAPT (0.70) | MAPTTP53SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11241812 | 0.79 | MAPT (0.63) | MAPTGAATP53PDE4BSMN1; SMN2 | |
| SCHEMBL20435782 | 0.79 | MAPT (0.61) | MAPTTHRBGAATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11242923 | 0.78 | MAPT (0.69) | MAPTTP53SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343804-A | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-08-10 | — | — | US | disclosed |