SCHEMBL11248322

SCHEMBL11248322

CC(C)c1ccc(-n2cc(C#N)c(=O)[nH]c2=O)cc1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.67
KMT2A Q03164 4/20 0.65
MEN1 O00255 1/20 0.65
GAA P10253 1/20 0.50
MCL1 Q07820 1/20 0.42
MGLL Q99685 1/20 0.41
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
NPBWR1 P48145 1/20 0.38
MCHR1 Q99705 1/20 0.38
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11268300 0.84 L3MBTL1 (0.72) L3MBTL1KMT2AMEN1GAAMCL1
SCHEMBL11245813 0.84 L3MBTL1 (0.68) L3MBTL1KMT2AMEN1GAAMCL1
SCHEMBL11246293 0.82 L3MBTL1 (0.69) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11237480 0.81 L3MBTL1 (0.68) L3MBTL1KMT2AMEN1GAAMGLL
SCHEMBL11254345 0.81 L3MBTL1 (0.68) L3MBTL1KMT2AMEN1GAAMCL1
SCHEMBL11248370 0.80 L3MBTL1 (0.67) L3MBTL1KMT2AMEN1GAAMCL1
SCHEMBL11247073 0.80 L3MBTL1 (0.67) L3MBTL1KMT2AMEN1GAAMCL1
SCHEMBL11239058 0.80 L3MBTL1 (0.67) L3MBTL1KMT2AMEN1GAAMGLL
SCHEMBL11237396 0.80 L3MBTL1 (1.00) L3MBTL1KMT2AMEN1GAAMGLL
SCHEMBL11244000 0.80 L3MBTL1 (0.67) L3MBTL1KMT2AMEN1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358591-A BACTERICIDES, FUNGICIDES; PLANT DISEASES ZOECON CORPORATION (US) 1982-11-09 US disclosed
US-4338318-A FUNGICIDE OR BACERICIDE TO TREAT PLANT DISEASES WITH A PHENYL URACIL ZOECON CORPORATION (US) 1982-07-06 US disclosed
US-4307098-A 2-PHENYL-URACIL COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-12-22 US disclosed
US-4297297-A α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates ZOECON CORP. (US) 1981-10-27 US disclosed
US-4266056-A FUNGICIDES, BACTERICIDES ZOECON CORPORATION (US) 1981-05-05 US disclosed