SCHEMBL11245813

SCHEMBL11245813

N#Cc1cn(-c2ccc(Cl)cc2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.68
KMT2A Q03164 8/20 0.66
MEN1 O00255 5/20 0.66
GAA P10253 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.42
MCL1 Q07820 1/20 0.41
ALDH1A1 P00352 6/20 0.41
KDM4E B2RXH2 4/20 0.41
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
MGLL Q99685 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11246293 0.86 L3MBTL1 (0.69) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11249006 0.86 L3MBTL1 (0.57) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11254345 0.84 L3MBTL1 (0.68) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11268300 0.84 L3MBTL1 (0.72) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11237480 0.84 L3MBTL1 (0.68) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11248370 0.84 L3MBTL1 (0.67) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11255394 0.84 L3MBTL1 (0.56) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL8888929 0.84 L3MBTL1 (0.59) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11248322 0.84 L3MBTL1 (0.67) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL8888355 0.83 L3MBTL1 (0.55) L3MBTL1KMT2AMEN1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358591-A BACTERICIDES, FUNGICIDES; PLANT DISEASES ZOECON CORPORATION (US) 1982-11-09 US disclosed
US-4338318-A FUNGICIDE OR BACERICIDE TO TREAT PLANT DISEASES WITH A PHENYL URACIL ZOECON CORPORATION (US) 1982-07-06 US disclosed
US-4307098-A 2-PHENYL-URACIL COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-12-22 US disclosed
US-4297297-A α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates ZOECON CORP. (US) 1981-10-27 US disclosed
US-4266056-A FUNGICIDES, BACTERICIDES ZOECON CORPORATION (US) 1981-05-05 US disclosed