Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 10/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11464169 | 0.73 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL11245760 | 0.72 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL2325739 | 0.69 | ADRA2C (0.81) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL14995405 | 0.69 | PIK3CA (0.37) | — | |
| SCHEMBL11461605 | 0.68 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL8022622 | 0.68 | ADRA2A (0.65) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL11462519 | 0.68 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| Hydrochloric Acid SCHEMBL16244556 | 0.67 | PIK3CD (0.36) | — | |
| SCHEMBL11468081 | 0.67 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL9100635 | 0.67 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323570-A | HYPOTENSIVE AGENTS AND TREATING GLAUCOMA | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1982-04-06 | — | — | US | disclosed |