Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240630 | 0.86 | CYP2C9 (0.37) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL5523699 | 0.71 | KMT2A (0.39) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL17169742 | 0.67 | KMT2A (0.39) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| Phenolsulfonphthalein SCHEMBL17836 | 0.67 | MEN1 (1.00) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| Phenolsulfonphthalein SCHEMBL29357178 | 0.67 | MEN1 (1.00) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL446104 | 0.66 | KMT2A (0.38) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| Phenolsulfonphthalein SCHEMBL1157401 | 0.66 | MEN1 (0.97) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL10049655 | 0.64 | KMT2A (0.50) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL29508189 | 0.64 | KMT2A (0.50) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL7685977 | 0.63 | KMT2A (0.35) | MEN1KMT2ALMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359574-A | Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives | POLAROID CORPORATION (US) | 1982-11-16 | — | — | US | disclosed |
| US-4311839-A | Benzisothiazole and naphtho-1,2-thiazine compounds | POLAROID CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4283537-A | Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives and process for preparation | POLAROID CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4259498-A | Process for preparing benzisothiazole-1,1-dioxide and naphtho-1,2-thiazine-1,1-dioxide compounds | POLAROID CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| US-4255578-A | Synthesis of perhalomethylcarbinol-substituted phenol and naphthol sulfamphthalein dyes from the corresponding triacylated derivatives | POLAROID CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4231929-A | Sulfam(na)phthaleins | POLAROID CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4228075-A | Novel sulfam(na)phthaleins | POLAROID CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |
| US-4210752-A | Synthesis of substituted sulfam(na)phthaleins | POLAROID CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| US-4204061-A | Sulfam(na)phthaleins | POLAROID CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |
| US-4195180-A | Sulfam (na) phthaleins | POLAROID CORPORATION (US) | 1980-03-25 | — | — | US | disclosed |
| US-4191689-A | Benzisothiazole-1,1-dioxide and naphtho-1,2-thiazine-1,1-dioxide compounds | POLAROID CORPORATION (US) | 1980-03-04 | — | — | US | disclosed |
| US-4178446-A | Sulfam(na)phthaleins | POLAROID CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |
| US-4178447-A | Novel synthesis of 3,3-substituted dihydrobenzisothiazole-1,1-dioxides and -2,3-dihydronaphtho-1,2-thiazine-1,1-dioxides | POLAROID CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |