Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 7/20 | 0.35 |
| ▸ | CA9 | Q16790 | 7/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA4 | P22748 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 4/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448460 | 0.75 | KMT2A (0.39) | KMT2AMEN1NOX1CA12CA9 | |
| Ammonia Solution, Strong SCHEMBL446104 | 0.73 | KMT2A (0.38) | KMT2AMEN1NOX1CA12CA9 | |
| SCHEMBL31536393 | 0.72 | PKM (0.35) | KMT2AMEN1GAAKDM4EPKM | |
| SCHEMBL5523699 | 0.71 | KMT2A (0.39) | KMT2AMEN1NOX1CA12CA9 | |
| SCHEMBL17169742 | 0.71 | KMT2A (0.39) | KMT2AMEN1NOX1CA12CA9 | |
| SCHEMBL26048255 | 0.71 | KMT2A (0.39) | KMT2AMEN1NOX1CA12CA9 | |
| SCHEMBL11240630 | 0.68 | CYP2C9 (0.37) | KMT2AMEN1NOX1CA12CA9 | |
| SCHEMBL2202766 | 0.66 | PDE7A (0.39) | KMT2AMEN1PDE7A | |
| SCHEMBL28234767 | 0.66 | KMT2A (0.34) | KMT2AMEN1NOX1CA12CA9 | |
| SCHEMBL28241763 | 0.66 | KMT2A (0.34) | KMT2AMEN1NOX1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |
| US-6300354-B1 | FOR THERAPY OF NEUROLEPTIC DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-09 | — | — | US | disclosed |