SCHEMBL11240630

SCHEMBL11240630

O=S1(=O)NC(c2ccccc2)(c2ccccc2)c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.37
CACNA1F O60840 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
HTR2A P28223 1/20 0.37
HRH1 P35367 1/20 0.37
SCN1A P35498 1/20 0.37
SCN4A P35499 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
CACNA1D Q01668 1/20 0.37
KCNH2 Q12809 1/20 0.37
CACNA1S Q13698 1/20 0.37
CACNA1C Q13936 1/20 0.37
SCN5A Q14524 1/20 0.37
SCN2A Q99250 1/20 0.37
SCN3A Q9NY46 1/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
NOX1 Q9Y5S8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11248429 0.86 MEN1 (0.50) CYP2C9ALDH1A1MAPTKCNH2KMT2A
SCHEMBL5523699 0.72 KMT2A (0.39) CYP2C9ALDH1A1KMT2AMEN1NOX1
SCHEMBL17169742 0.72 KMT2A (0.39) CYP2C9CACNA1FCACNA1DCACNA1SCACNA1C
SCHEMBL448460 0.72 KMT2A (0.39) CYP2C9ALDH1A1MAPTKMT2AMEN1
SCHEMBL26048255 0.72 KMT2A (0.39) CYP2C9KMT2AMEN1NOX1CA12
Ammonia Solution, Strong SCHEMBL446104 0.71 KMT2A (0.38) CYP2C9ALDH1A1MAPTKMT2AMEN1
SCHEMBL11128885 0.70 SLC40A1 (0.31) MAPTKMT2AKDM4E
SCHEMBL7685977 0.68 KMT2A (0.35) KMT2AMEN1NOX1CA12CA1
SCHEMBL28241763 0.67 KMT2A (0.34) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL28234767 0.67 KMT2A (0.34) KMT2AMEN1NOX1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242495-A1 Nitrosation Reagents and Methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-08-03 US disclosed
US-20230242495-A1 Nitrosation Reagents and Methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-08-03 US disclosed
US-10026983-B2 Polymer electrolyte material, polymer electrolyte molded product using the polymer electrolyte material and method for manufacturing the polymer electrolyte molded product, membrane electrode composite, and solid polymer fuel cell TORAY INDUSTRIES, INC. (JP) 2018-07-17 US disclosed
US-10026983-B2 Polymer electrolyte material, polymer electrolyte molded product using the polymer electrolyte material and method for manufacturing the polymer electrolyte molded product, membrane electrode composite, and solid polymer fuel cell TORAY INDUSTRIES, INC. (JP) 2018-07-17 US disclosed
EP-1641063-B1 POLYMER ELECTROLYTE, POLYMER ELECTROLYTE MEMBRANE THEREFROM, MEMBRANE ELECTRODE ASSEMBLY AND POLYMER ELECTROLYTE FUEL CELL TORAY INDUSTRIES (JP) 2018-06-20 EP disclosed
US-20170222243-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE MOLDED PRODUCT USING THE POLYMER ELECTROLYTE MATERIAL AND METHOD FOR MANUFACTURING THE POLYMER ELECTROLYTE MOLDED PRODUCT, MEMBRANE ELECTRODE COMPOSITE, AND SOLID POLYMER FUEL CELL TORAY INDUSTRIES, INC. 2017-08-03 US disclosed
US-20170222243-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE MOLDED PRODUCT USING THE POLYMER ELECTROLYTE MATERIAL AND METHOD FOR MANUFACTURING THE POLYMER ELECTROLYTE MOLDED PRODUCT, MEMBRANE ELECTRODE COMPOSITE, AND SOLID POLYMER FUEL CELL TORAY INDUSTRIES, INC. 2017-08-03 US disclosed
EP-2758448-B1 SULFONIC ACID GROUP-CONTAINING POLYMER, SULFONIC ACID GROUP-CONTAINING AROMATIC COMPOUND AND METHOD OF MAKING THE SAME, AS WELL AS POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE MOLDED PRODUCT AND SOLID POLYMER FUEL CELL USING THE SAME TORAY INDUSTRIES (JP) 2017-08-02 EP disclosed
US-9701789-B2 Sulfonic acid group-containing polymer, sulfonic acid group-containing aromatic compound and method of making the same, as well as polymer electrolyte material, polymer electrolyte molded product and solid polymer fuel cell using the same TORAY INDUSTRIES, INC. (JP) 2017-07-11 US disclosed
US-9701789-B2 Sulfonic acid group-containing polymer, sulfonic acid group-containing aromatic compound and method of making the same, as well as polymer electrolyte material, polymer electrolyte molded product and solid polymer fuel cell using the same TORAY INDUSTRIES, INC. (JP) 2017-07-11 US disclosed
US-20070134530-A1 Polymer electrolyte as well as polymer electrolyte membrane, membrane electrode assembly and polymer electrolyte fuel cell using the same TORAY INDUSTRIES, INC. (JP) 2007-06-14 US disclosed
US-20070134530-A1 Polymer electrolyte as well as polymer electrolyte membrane, membrane electrode assembly and polymer electrolyte fuel cell using the same TORAY INDUSTRIES, INC. (JP) 2007-06-14 US disclosed
US-4359574-A Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives POLAROID CORPORATION (US) 1982-11-16 US disclosed
US-4311839-A Benzisothiazole and naphtho-1,2-thiazine compounds POLAROID CORPORATION (US) 1982-01-19 US disclosed
US-4283537-A Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives and process for preparation POLAROID CORPORATION (US) 1981-08-11 US disclosed
US-4259498-A Process for preparing benzisothiazole-1,1-dioxide and naphtho-1,2-thiazine-1,1-dioxide compounds POLAROID CORPORATION (US) 1981-03-31 US disclosed
US-4255578-A Synthesis of perhalomethylcarbinol-substituted phenol and naphthol sulfamphthalein dyes from the corresponding triacylated derivatives POLAROID CORPORATION (US) 1981-03-10 US disclosed
US-4210752-A Synthesis of substituted sulfam(na)phthaleins POLAROID CORPORATION (US) 1980-07-01 US disclosed
US-4191689-A Benzisothiazole-1,1-dioxide and naphtho-1,2-thiazine-1,1-dioxide compounds POLAROID CORPORATION (US) 1980-03-04 US disclosed
US-4178447-A Novel synthesis of 3,3-substituted dihydrobenzisothiazole-1,1-dioxides and -2,3-dihydronaphtho-1,2-thiazine-1,1-dioxides POLAROID CORPORATION (US) 1979-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242495-A1 Nitrosation Reagents and Methods NOS2, NOS1, NNMT CYP2C9 261/4885CACNA1F 3259/4885ALDH1A1 535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.