SCHEMBL10049655

SCHEMBL10049655

O=C1NC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
MEN1 O00255 4/20 0.50
MAPT P10636 3/20 0.50
ALDH1A1 P00352 3/20 0.50
LMNA P02545 3/20 0.50
GPR55 Q9Y2T6 3/20 0.50
HSD17B10 Q99714 2/20 0.50
ESR1 P03372 1/20 0.50
TP53 P04637 1/20 0.50
TYMS P04818 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ESR2 Q92731 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
AKR1B1 P15121 1/20 0.50
CHRM2 P08172 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
KCNH2 Q12809 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29508189 1.00 KMT2A (0.50) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL17814220 0.90 KMT2A (0.42) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL11990851 0.85 ITGA4 (0.48) MAPTALDH1A1LMNAHSD17B10AKR1B1
SCHEMBL10049648 0.83 ITGA4 (0.43) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL13668299 0.81 AGTR1 (0.45) KMT2AMAPTALDH1A1LMNASMN1; SMN2
SCHEMBL17813126 0.80 ITGA4 (0.41) KMT2AMAPTALDH1A1HSD17B10CYP3A4
SCHEMBL22268171 0.79 TNKS2 (0.47) KMT2AMEN1MAPTALDH1A1HSD17B10
SCHEMBL17814239 0.79 ATM (0.47) KMT2AMEN1MAPTALDH1A1TP53
SCHEMBL8143530 0.79 ESR1 (0.57) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL8150324 0.79 DHFR (0.48) KMT2AMEN1MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002534-A1 POLYESTER-POLYCARBONATE COPOLYMER AND METHOD FOR PRODUCING SAME SAMYANG CORPORATION (KR) 2023-01-05 US disclosed
US-20210403661-A1 PLASTIC FILMS HAVING HIGH VICAT SOFTENING TEMPERATURE IN LAYERED STRUCTURES COVESTRO DEUTSCHLAND AG (DE) 2021-12-30 US disclosed
EP-3856841-A1 POLYCARBONATE COMPOSITION AND ASSOCIATED ARTICLE AND METHOD OF ADDITIVE MANUFACTURING SHPP Global Technologies B.V. (NL) 2021-08-04 EP disclosed
US-20200291162-A1 POLYESTER-POLYCARBONATE COPOLYMER AND METHOD FOR PRODUCING SAME SAMYANG CORPORATION (KR) 2020-09-17 US disclosed
WO-2020068164-A1 POLYCARBONATE COMPOSITION AND ASSOCIATED ARTICLE AND METHOD OF ADDITIVE MANUFACTURING SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-04-02 WO disclosed
EP-2155820-B1 POLYARYL ETHER KETONE-POLYCARBONATE COPOLYMER BLENDS SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-02-01 EP disclosed
US-9127126-B2 Development of high-viscosity bonding layer through in-situ polymer chain extension BREWER SCIENCE INC. (US) 2015-09-08 US disclosed
US-20130288058-A1 DEVELOPMENT OF HIGH-VISCOSITY BONDING LAYER THROUGH IN-SITU POLYMER CHAIN EXTENSION BREWER SCIENCE INC. (US) 2013-10-31 US disclosed
US-20120041102-A1 NOVEL EPOXY RESIN AND EPOXY RESIN COMPOSITION COMPRISING THE SAME KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2012-02-16 US disclosed
US-20120041102-A1 NOVEL EPOXY RESIN AND EPOXY RESIN COMPOSITION COMPRISING THE SAME KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2012-02-16 US disclosed