Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912928 | 0.77 | HTR2A (0.65) | HTR2AHTR2CIMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL27434539 | 0.74 | ALDH1A1 (0.38) | HTR2AHTR2CALDH1A1TSHRKDM4E | |
| SCHEMBL2009406 | 0.72 | KDM4E (0.60) | HTR2AHTR2CIMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL31060568 | 0.71 | HTR2A (1.00) | HTR2AHTR2CIMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL18509955 | 0.70 | HTR2A (0.63) | HTR2AHTR2CALDH1A1KDM4EPOLB | |
| SCHEMBL6009679 | 0.69 | IMPDH2 (0.57) | HTR2AHTR2CIMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL933915 | 0.69 | HTR2A (0.54) | HTR2AHTR2CIMPDH2IMPDH1TSHR | |
| SCHEMBL17164006 | 0.69 | ALDH1A1 (0.46) | HTR2AHTR2CALDH1A1TSHRHTR2B | |
| SCHEMBL11063026 | 0.68 | HSPA5 (0.34) | ALDH1A1TSHRPOLBCYP3A4LMNA | |
| SCHEMBL5770077 | 0.68 | GRIN2D (0.39) | IMPDH2IMPDH1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317832-A | ADRENERGIC BLOCKING AGENTS; HYPOTENSIVE AGENTS | KLINGLER KARL HEINZ | 1982-03-02 | — | — | US | disclosed |