Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710814 | 0.87 | DRD2 (0.65) | DRD2DRD1KCNH2BCHEACHE | |
| Hydrochloric Acid SCHEMBL11708619 | 0.86 | DRD2 (0.64) | DRD2DRD1KCNH2BCHEACHE | |
| SCHEMBL11712556 | 0.79 | BCHE (0.63) | DRD2DRD1KCNH2BCHEACHE | |
| Hydrochloric Acid SCHEMBL11707551 | 0.78 | DRD2 (0.60) | DRD2DRD1KCNH2BCHEACHE | |
| SCHEMBL14740349 | 0.77 | DRD2 (0.61) | DRD2DRD1DRD3SIGMAR1 | |
| SCHEMBL11710629 | 0.75 | DRD2 (0.64) | DRD2DRD1KCNH2BCHEACHE | |
| SCHEMBL13232384 | 0.74 | LMNA (0.73) | KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL11638212 | 0.74 | LMNA (0.73) | KDM4EALDH1A1ALOX15HSD17B10 | |
| Bromide SCHEMBL11715068 | 0.74 | DRD2 (0.62) | DRD2DRD1KCNH2BCHEACHE | |
| SCHEMBL462517 | 0.74 | DRD2 (0.65) | DRD2DRD1KCNH2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309542-A | WITH A TRIMETHYLPHENYLAMMONIUM BASE | WARNER-LAMBERT COMPANY (US) | 1982-01-05 | — | — | US | disclosed |