Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25197137 | 0.87 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL7046987 | 0.87 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL2127920 | 0.82 | KMT2A (0.66) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL9729410 | 0.82 | KMT2A (0.76) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL6353463 | 0.81 | KDM4E (0.42) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL10882250 | 0.81 | KMT2A (0.64) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL9828028 | 0.80 | MEN1 (0.62) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL27238307 | 0.79 | GAA (0.49) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL3407396 | 0.78 | MEN1 (0.65) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL25238149 | 0.78 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000382-B1 | PYRIMIDO (4,5-C)PYRIDAZINES, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-10-06 | — | — | EP | disclosed |
| US-4315932-A | AND SULFANILAMIDES | BURROUGHS WELLCOME CO. (US) | 1982-02-16 | — | — | US | disclosed |
| EP-0000541-B1 | 1H-PYRIMIDO-(4,5-C)-1,2-DIAZEPINES, METHODS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM; THEIR USE AS INTERMEDIATES FOR HETEROCYCLIC TRANSFORMATIONS. | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-02-03 | — | — | EP | disclosed |
| US-4288365-A | 1H-PYRIMIDO(4,5-C)-1,2-DIAZEPINES | BURROUGHS WELLCOME CO. (US) | 1981-09-08 | — | — | US | disclosed |
| US-4260758-A | MICROBIOCIDES | BURROUGHS WELLCOME CO. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4255427-A | TREATMENT OF COCCIDIOSIS IN POULTRY | BURROUGHS WELLCOME CO. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4237289-A | MICROBIOCIDES | BURROUGHS WELLCOME CO. (US) | 1980-12-02 | — | — | US | disclosed |
| EP-0000382-A1 | Pyrimido (4,5-c)pyridazines, compositions containing them and processes for their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-01-24 | — | — | EP | disclosed |