Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7122394 | 0.94 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL8430195 | 0.91 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL27823832 | 0.88 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL8430188 | 0.88 | TSHR (0.66) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL8430187 | 0.87 | BPTF (0.56) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9828028 | 0.86 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7046987 | 0.86 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7837299 | 0.85 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL25238149 | 0.84 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9702085 | 0.84 | PKM (0.62) | MEN1KMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661902-B1 | METHOD FOR THE DEACYLATION AND/OR DEALKYLATION OF COMPOUNDS | UNIV ANTWERPEN (BE) | 2025-07-16 | — | — | EP | claimed |
| US-20210130273-A1 | METHOD FOR THE DEACYLATION AND/OR DEALKYLATION OF COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2021-05-06 | — | — | US | claimed |
| CN-111542509-A | Method for deacylation and/or dealkylation of compounds | 安特卫普大学 | 2020-08-14 | — | — | CN | claimed |
| EP-3661902-A1 | METHOD FOR THE DEACYLATION AND/OR DEALKYLATION OF COMPOUNDS | Universiteit Antwerpen (BE) | 2020-06-10 | — | — | EP | claimed |
| WO-2019025535-A1 | METHOD FOR THE DEACYLATION AND/OR DEALKYLATION OF COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2019-02-07 | — | — | WO | claimed |
| EP-3661902-B1 | METHOD FOR THE DEACYLATION AND/OR DEALKYLATION OF COMPOUNDS | UNIV ANTWERPEN (BE) | 2025-07-16 | — | — | EP | disclosed |
| CN-110526854-B | Alpha, beta-unsaturated ketone derivative, preparation method and application thereof as medicine | 宁夏医科大学 | 2023-12-15 | — | — | CN | disclosed |
| EP-3904330-A1 | ETHYLENEDIAMINE COMPOUND AND USE THEREOF | Academy Of Military Medical Sciences (CN) | 2021-11-03 | — | — | EP | disclosed |
| US-20210130273-A1 | METHOD FOR THE DEACYLATION AND/OR DEALKYLATION OF COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2021-05-06 | — | — | US | disclosed |
| WO-2021017795-A1 | α,β-UNSATURATED KETONE DERIVATIVE, PREPARATION METHOD AND USE AS MEDICINE | 宁夏医科大学 | 2021-02-04 | — | — | WO | disclosed |
| WO-2021017795-A1 | α,β-UNSATURATED KETONE DERIVATIVE, PREPARATION METHOD AND USE AS MEDICINE | 宁夏医科大学 | 2021-02-04 | — | — | WO | disclosed |
| CN-108299458-B | Oridonin derivative and preparation method and application thereof | 青岛海洋生物医药研究院股份有限公司 | 2020-10-02 | — | — | CN | disclosed |
| EP-0680950-B1 | PROPENONE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5952355-A | 1-ETHER-SUBSTITUTED PHENYL-3-INDOL-3-YL-2-PROPEN-1-ONE DERIVATIVES; ANTITUMOR AND -CARCINOGENIC AGENTS; IMMUNOSUPPRESSANTS; AUTOIMMUNE DISEASES; SIDE EFFECT REDUCTION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0812825-A1 | PROPENONE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |
| EP-0680950-A1 | PROPENONE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-11-08 | — | — | EP | disclosed |
| EP-0322033-A2 | New 2,5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1989-06-28 | — | — | EP | disclosed |
| US-4757084-A | Pharmaceuticals | MERCK & CO., INC. (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0217204-A1 | Trans-2-(3,4,5-trimethoxyphenyl)-5-(5,6-dimethoxy-3-pyridyl)-tetrahydrothiophene, a PAF-antagonist | MERCK & CO. INC. (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0154887-A1 | New 2,5-diaryl tetrahydrothiophenes and analogs thereof as paf-antagonists | MERCK & CO. INC. (US) | 1985-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130273-A1 | METHOD FOR THE DEACYLATION AND/OR DEALKYLATION OF COMPOUNDS | HAAO, TDO2, HPD | MEN1 3750/4885KMT2A 1208/4885ALDH1A1 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.