Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2F2 | P24468 | 3/20 | 0.52 |
| ▸ | GALR3 | O60755 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245912 | 0.87 | ABCG2 (0.53) | NR2F2GALR3SMN1; SMN2MAPK1GAA | |
| SCHEMBL11256846 | 0.83 | NR2F2 (0.59) | NR2F2GALR3SMN1; SMN2MAPK1HTT | |
| SCHEMBL11254153 | 0.82 | LDHA (0.61) | NR2F2GALR3SMN1; SMN2MAPK1GAA | |
| SCHEMBL11250025 | 0.82 | NPC1 (0.52) | NR2F2GALR3SMN1; SMN2MAPK1HTT | |
| SCHEMBL11104898 | 0.80 | ADRB2 (0.42) | SMN1; SMN2ALOX15HTTRAB9ANPC1 | |
| SCHEMBL11240075 | 0.79 | EGFR (0.53) | NR2F2GALR3SMN1; SMN2MAPK1HTT | |
| SCHEMBL11255628 | 0.79 | GBA1 (0.56) | NR2F2GALR3SMN1; SMN2MAPK1HTT | |
| SCHEMBL11248882 | 0.79 | EGFR (0.52) | NR2F2GALR3SMN1; SMN2HTTLDHA | |
| SCHEMBL13283199 | 0.78 | GALR3 (0.63) | NR2F2GALR3SMN1; SMN2MAPK1GAA | |
| SCHEMBL4572178 | 0.78 | GALR3 (0.63) | NR2F2GALR3SMN1; SMN2MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |