Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 3/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.46 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659667 | 0.92 | GCGR (0.60) | GCGRTDP1PNLIPS1PR1KDR | |
| SCHEMBL11256032 | 0.90 | GCGR (0.58) | GCGRTDP1PNLIPS1PR1KDR | |
| SCHEMBL11239027 | 0.86 | GCGR (0.51) | GCGRTDP1S1PR1KDRPLCG2 | |
| SCHEMBL11246898 | 0.86 | PNLIP (0.52) | GCGRTDP1PNLIPS1PR1KDR | |
| SCHEMBL11249648 | 0.86 | GCGR (0.52) | GCGRTDP1PNLIPS1PR1KDR | |
| SCHEMBL11244163 | 0.84 | PNLIP (0.51) | GCGRTDP1PNLIPS1PR1KDR | |
| SCHEMBL11248306 | 0.84 | PNLIP (0.51) | GCGRTDP1PNLIPS1PR1KDR | |
| SCHEMBL11256445 | 0.84 | GCGR (0.50) | GCGRTDP1S1PR1KDRPLCG2 | |
| SCHEMBL11245283 | 0.84 | GCGR (0.50) | GCGRTDP1PNLIPS1PR1STK39 | |
| SCHEMBL9628562 | 0.82 | KMT2A (0.66) | GCGRTDP1PNLIPS1PR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025363-B1 | N-BENZOYL N'-PYRIDYLOXY PHENYL UREAS, A PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL AND INSECTICIDAL COMPOSITIONS CONTAINING THE SAME | ISHIHARA SANGYO KAISHA LTD. (JP) | 1982-08-25 | — | — | EP | disclosed |
| US-4321388-A | N-benzoyl N'-pyridyloxy phenyl urea | ISHIHARA SANGYO KAISHA LTD. (JP) | 1982-03-23 | — | — | US | disclosed |
| EP-0025363-A1 | N-Benzoyl N'-pyridyloxy phenyl ureas, a process for their production and pharmaceutical and insecticidal compositions containing the same | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-03-18 | — | — | EP | disclosed |