Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266201 | 0.89 | OPRK1 (0.47) | SMN1; SMN2HTR2AHTR2COPRK1PDE4D | |
| Hydrochloric Acid SCHEMBL11431914 | 0.83 | OPRK1 (0.56) | HPGDHTR2COPRK1PDE4DADRA1A | |
| SCHEMBL10858544 | 0.78 | OPRK1 (0.38) | HRH4HTR2AHTR2CHTR1AHTR7 | |
| SCHEMBL11266170 | 0.73 | HPGD (0.51) | HPGDSMN1; SMN2HTR2AHTR2CHTR1A | |
| SCHEMBL11251836 | 0.73 | OPRK1 (0.49) | HPGDHTR2COPRK1PDE4DADRA1A | |
| Hydrochloric Acid SCHEMBL11251814 | 0.73 | EBP (0.43) | HTR2COPRK1PDE4DADRA1ANR1I2 | |
| Hydrochloric Acid SCHEMBL11255176 | 0.72 | OPRK1 (0.40) | HTR2AHTR2CHTR2BOPRK1PDE4D | |
| SCHEMBL9652997 | 0.72 | CCKBR (0.46) | HTR2AHTR2CHTR1AHTR1DHTR7 | |
| Hydrochloric Acid SCHEMBL11248904 | 0.71 | OPRK1 (0.40) | HPGDHTR2AHTR2CHTR2BOPRK1 | |
| SCHEMBL11261476 | 0.70 | OPRK1 (0.45) | SMN1; SMN2HTR2AHTR2COPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338314-A | [1,2]Anellated-7-phenyl-1,4-benzodiazepine and pharmaceutical compositions thereof and use for treatment of ulcers | KALI-CHEMIE PHARMA GMBH (DE) | 1982-07-06 | — | — | US | disclosed |