Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18042666 | 0.94 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL19692314 | 0.86 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL1476747 | 0.86 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL1611049 | 0.86 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL1476715 | 0.86 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL19691908 | 0.86 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL14863743 | 0.81 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL2966938 | 0.81 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL2961154 | 0.81 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL16411469 | 0.78 | ALOX5 (0.55) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002938-B1 | NOVEL HETEROCYCLIC CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| EP-0002939-B1 | NOVEL CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |
| EP-0003081-B1 | THIAZOLIDINECARBOTHIOAMIDES, THEIR PREPARATION, COMPOSITIONS AND USE AS INSECTICIDES | ELI LILLY AND COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4289778-A | SYSTEMIC INSECTICIDES | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| US-4289766-A | Heterocyclic carbothioamides | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| US-4195092-A | INSECTICIDES FOR TREATING MEXICAN BEAN BEETLE | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| EP-0003081-A2 | Thiazolidinecarbothioamides, their preparation, compositions and use as insecticides | ELI LILLY AND COMPANY (US) | 1979-07-25 | — | — | EP | disclosed |
| EP-0002939-A2 | Novel carbothioamides, compositions containing them and their preparation | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |
| EP-0002938-A2 | Novel heterocyclic carbothioamides, compositions containing them, their preparation and use | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |