SCHEMBL1476747

SCHEMBL1476747

[CH2]CCCCCCCCCC1CC1CCCCCC

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.55
ALDH1A1 P00352 1/20 0.41
EPHX1 P07099 1/20 0.39
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
GBA1 P04062 3/20 0.32
NOS1 P29475 3/20 0.32
NOS2 P35228 3/20 0.32
CYP1A2 P05177 2/20 0.32
NOS3 P29474 2/20 0.32
TRPV1 Q8NER1 2/20 0.32
SPHK1 Q9NYA1 3/20 0.32
SPHK2 Q9NRA0 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19691908 1.00 ALOX5 (0.55) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL19692314 1.00 ALOX5 (0.55) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL1611049 1.00 ALOX5 (0.55) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL1476715 1.00 ALOX5 (0.55) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL2961154 0.94 ALOX5 (0.50) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL2966938 0.94 ALOX5 (0.50) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL18657390 0.88 ALOX5 (0.65) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL29971764 0.88 ALOX5 (0.65) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL18685663 0.88 ALOX5 (0.65) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL9376923 0.87 ALOX5 (0.43) ALOX5ALDH1A1EPHX1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390378-B1 PHARMACEUTICALLY ACTIVE URIDINE ESTERS TROMMSDORFF ARZNEIMITTEL (DE) 2009-06-17 EP claimed
US-7396826-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2008-07-08 US claimed
US-20040121979-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2004-06-24 US claimed
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-03-17 US disclosed
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-08-27 US disclosed
EP-2827899-B1 POLYSACCHARIDE ANTIGEN-GLYCOLIPID CONJUGATE VACCINES MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) 2015-08-05 EP disclosed
CN-104321079-A Carbohydrate-glycolipid conjugate vaccines MAX PLANCK GESELLSCHAFT 2015-01-28 CN disclosed
US-7915234-B2 Synergistic mixture; antioxidant; cardiovascular disorders; antidiabetic agents TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2011-03-29 US disclosed
US-7560442-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2009-07-14 US disclosed
EP-1390378-B1 PHARMACEUTICALLY ACTIVE URIDINE ESTERS TROMMSDORFF ARZNEIMITTEL (DE) 2009-06-17 EP disclosed
US-7417034-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZENEIMITTEL (DE) 2008-08-26 US disclosed
US-7396826-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2008-07-08 US disclosed
EP-1666092-A2 Drug combination comprising a fatty acid and a uridine compound. Trommsdorff GmbH & Co.KG Arzneimittel (DE) 2006-06-07 EP disclosed
US-20050065110-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO., KG ARZNEIMITTEL 2005-03-24 US disclosed
US-20050043394-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL 2005-02-24 US disclosed
US-20050043269-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL 2005-02-24 US disclosed
US-20040121979-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2004-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043394-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR3 ALOX5 43/4885ALDH1A1 342/4885EPHX1 879/4885
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES STT3B, STT3A, DDOST ALOX5 2664/4885ALDH1A1 2693/4885EPHX1 3359/4885
US-20040121979-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR1 ALOX5 49/4885ALDH1A1 142/4885EPHX1 843/4885
US-20050043269-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR3 ALOX5 43/4885ALDH1A1 342/4885EPHX1 879/4885
US-20050065110-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR3 ALOX5 43/4885ALDH1A1 342/4885EPHX1 879/4885
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines STT3B, STT3A, DDOST ALOX5 2664/4885ALDH1A1 2693/4885EPHX1 3359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.