SCHEMBL19691908

SCHEMBL19691908

[CH2]CCCCCCC1CC1CCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.55
ALDH1A1 P00352 1/20 0.41
EPHX1 P07099 1/20 0.39
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
GBA1 P04062 3/20 0.32
NOS1 P29475 3/20 0.32
NOS2 P35228 3/20 0.32
CYP1A2 P05177 2/20 0.32
NOS3 P29474 2/20 0.32
TRPV1 Q8NER1 2/20 0.32
SPHK1 Q9NYA1 3/20 0.32
SPHK2 Q9NRA0 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19692314 1.00 ALOX5 (0.55) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL1611049 1.00 ALOX5 (0.55) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL1476715 1.00 ALOX5 (0.55) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL1476747 1.00 ALOX5 (0.55) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL2961154 0.94 ALOX5 (0.50) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL2966938 0.94 ALOX5 (0.50) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL18657390 0.88 ALOX5 (0.65) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL29971764 0.88 ALOX5 (0.65) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL18685663 0.88 ALOX5 (0.65) ALOX5ALDH1A1EPHX1TSHRTHRB
SCHEMBL9376923 0.87 ALOX5 (0.43) ALOX5ALDH1A1EPHX1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014512-A1 LYOPHILIZED COMPOSITION OF NUCLEIC-ACID-LOADED LIPID NANOPARTICLES 日油株式会社 2024-01-18 WO disclosed
WO-2024014511-A1 LIPID NANOPARTICLE AND METHOD FOR PRODUCING SAME, NUCLEIC ACID-ENCAPSULATED LIPID NANOPARTICLE AND METHOD FOR PRODUCING SAME, AND METHOD FOR INDUCING ACQUIRED IMMUNITY IN LIVING BODY BY USING NUCLEIC ACID-ENCAPSULATED LIPID NANOPARTICLE 日油株式会社 2024-01-18 WO disclosed
WO-2023190176-A1 LIPID NANOPARTICLES FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE, AND METHOD FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE USING SAME 日油株式会社 2023-10-05 WO disclosed
WO-2023190175-A1 LIPID NANOPARTICLES FOR DELIVERING NUCLEIC ACID TO PERIPHERAL BLOOD MONONUCLEAR CELLS, AND METHOD FOR DELIVERING NUCLEIC ACID TO PERIPHERAL BLOOD MONONUCLEAR CELLS USING SAME 日油株式会社 2023-10-05 WO disclosed
WO-2023190170-A1 METHOD FOR PRODUCING NUCLEIC ACID-ENCAPSULATED LIPID NANOPARTICLES, METHOD FOR PRODUCING PHARMACEUTICAL COMPOSITION CONTAINING SAID LIPID NANOPARTICLES, AND METHOD FOR INTRODUCING NUCLEIC ACID INTO CELL OR TARGET CELL 日油株式会社 2023-10-05 WO disclosed
US-20190336611-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CUREVAC AG (DE) 2019-11-07 US disclosed
EP-3468608-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac AG (DE) 2019-04-17 EP disclosed
WO-2017212006-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CUREVAC AG (DE) 2017-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190336611-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO PHAX, LNPEP, PITPNB ALOX5 3408/4885ALDH1A1 4507/4885EPHX1 3429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.