Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240120 | 0.83 | MEN1 (0.43) | MEN1KMT2AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL29904571 | 0.82 | CDK2 (0.46) | TRPV4KDM4ESMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL3133065 | 0.82 | CDK2 (0.46) | TRPV4KDM4ESMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL11217498 | 0.81 | NR1H2 (0.43) | MEN1KMT2AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL29500393 | 0.80 | MEN1 (0.56) | TRPV4MEN1KMT2ASLC22A12RXFP1 | |
| SCHEMBL65955 | 0.80 | MEN1 (0.56) | TRPV4MEN1KMT2ASLC22A12RXFP1 | |
| Fluoride SCHEMBL11240128 | 0.80 | TTR (0.53) | MEN1KMT2AKDM4ESMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL11248867 | 0.80 | TTR (0.53) | MEN1KMT2AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL17850502 | 0.79 | TRPV4 (0.44) | TRPV4MEN1KMT2ASLC22A12RXFP1 | |
| SCHEMBL6240708 | 0.79 | CCR4 (0.44) | TRPV4MEN1KMT2ASLC22A12RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331613-A | Process for the preparation of trifluoromethylnaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |