Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11248867 | 0.96 | TTR (0.53) | TTRCYP1A2MEN1KMT2AAURKA | |
| SCHEMBL11240120 | 0.81 | MEN1 (0.43) | MEN1KMT2ASLC22A12CDK2HSD11B1 | |
| SCHEMBL12355063 | 0.81 | TTR (0.56) | TTRCYP1A2MEN1KMT2AAURKA | |
| SCHEMBL11230600 | 0.81 | TTR (0.38) | TTRCYP1A2MEN1KMT2AAURKA | |
| SCHEMBL29363198 | 0.80 | TTR (0.75) | TTRCYP1A2MEN1KMT2AAURKA | |
| SCHEMBL6242 | 0.80 | TTR (0.75) | TTRCYP1A2MEN1KMT2AAURKA | |
| SCHEMBL30233642 | 0.80 | TTR (0.75) | TTRCYP1A2MEN1KMT2AAURKA | |
| SCHEMBL11217498 | 0.80 | NR1H2 (0.43) | MEN1KMT2ASLC22A12HSD11B1SLC9A1 | |
| SCHEMBL11248862 | 0.80 | TRPV4 (0.42) | MEN1KMT2ASLC22A12CDK2HSD11B1 | |
| SCHEMBL29624178 | 0.79 | KMT2A (0.56) | MEN1KMT2ASLC22A12HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331613-A | Process for the preparation of trifluoromethylnaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |