Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534511 | 0.86 | PGR (0.37) | HDAC3HDAC1HDAC8NCOR2MAOB | |
| SCHEMBL11049014 | 0.84 | MAOB (0.49) | CYP19A1MAOBMAOAALDH1A1 | |
| SCHEMBL19746 | 0.83 | CYP19A1 (0.45) | CYP19A1MAOBMAOAALDH1A1MAPT | |
| SCHEMBL11733122 | 0.82 | CYP19A1 (0.44) | CYP19A1MAOBMAOAALDH1A1MAPT | |
| SCHEMBL2283832 | 0.81 | CYP3A4 (0.49) | CYP19A1MAOBMAOANPC1MAPT | |
| SCHEMBL2474551 | 0.81 | MAOB (0.49) | CYP19A1MAOBMAOAKDM4EADORA3 | |
| SCHEMBL10381296 | 0.81 | POLB (0.42) | MAOBMAOAALDH1A1MAPTRAB9A | |
| SCHEMBL11259686 | 0.80 | ESR1 (0.40) | MAOBMAOAALDH1A1NPC1MAPT | |
| SCHEMBL127705 | 0.80 | MAPT (0.52) | CYP19A1MAOBABCB1MAOANPC1 | |
| Acetic Acid SCHEMBL11666716 | 0.79 | KMT2A (0.43) | CYP19A1MAOBALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025161-B1 | 3-METHYLENE FLAVANONES AND 3-METHYLENE CHROMANONES, ANTIMICROBIAL COMPOSITION CONTAINING SAME AND METHOD OF INHIBITING THE GROWTH OF MICROORGANISMS | MILES LABORATORIES, INC. (US) | 1982-06-09 | — | — | EP | disclosed |
| EP-0025161-A1 | 3-Methylene flavanones and 3-methylene chromanones, antimicrobial composition containing same and method of inhibiting the growth of microorganisms | MILES LABORATORIES, INC. (US) | 1981-03-18 | — | — | EP | disclosed |
| US-4241069-A | MICROBIOCIDES | MILES LABORATORIES, INC. (US) | 1980-12-23 | — | — | US | disclosed |