SCHEMBL11248969

SCHEMBL11248969

O=C(O)Cn1c(-c2ccccc2)c[nH]c1=O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.54
APEX1 P27695 1/20 0.51
KDM4E B2RXH2 7/20 0.49
HSD17B10 Q99714 4/20 0.49
ALDH1A1 P00352 4/20 0.49
HPGD P15428 4/20 0.49
GLA P06280 1/20 0.47
FPR1 P21462 1/20 0.43
FPR2 P25090 1/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8559809 0.81 NQO2 (0.44) L3MBTL1APEX1
SCHEMBL11255916 0.80 FABP4 (0.54) APEX1KDM4EHSD17B10ALDH1A1GLA
SCHEMBL11258884 0.80 FABP4 (0.54) APEX1KDM4EHSD17B10ALDH1A1GLA
SCHEMBL11267074 0.80 FABP4 (0.54) APEX1KDM4EHSD17B10ALDH1A1GLA
SCHEMBL11255610 0.80 FABP4 (0.54) APEX1KDM4EHSD17B10ALDH1A1GLA
SCHEMBL17446075 0.79 ALDH1A1 (0.65) L3MBTL1KDM4EHSD17B10ALDH1A1HPGD
SCHEMBL11125777 0.79 FABP4 (0.52) KDM4EHSD17B10ALDH1A1GLAKMT2A
SCHEMBL11125362 0.78 ALDH1A1 (0.55) KDM4EHSD17B10ALDH1A1HPGDKMT2A
SCHEMBL17446140 0.78 ALDH1A1 (0.54) KDM4EHSD17B10ALDH1A1HPGDKMT2A
SCHEMBL4494789 0.76 KDM4E (0.69) L3MBTL1APEX1KDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4330550-A ANTICOAGULANTS AND ANALGESICS A. NATTERMANN & CIE. GMBH (DE) 1982-05-18 US claimed