Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248969 | 0.81 | L3MBTL1 (0.54) | L3MBTL1APEX1 | |
| SCHEMBL7284267 | 0.69 | APEX1 (0.55) | NQO2WDR5ITGB3ITGA2BF2 | |
| SCHEMBL11246384 | 0.64 | ALDH1A1 (0.47) | APEX1 | |
| Hydrochloric Acid SCHEMBL14632476 | 0.64 | IDO1 (0.51) | — | |
| SCHEMBL7284365 | 0.63 | ITGB3 (0.47) | ITGB3ITGA2BF2PRSS1ALOX15 | |
| Acetic Acid SCHEMBL398148 | 0.63 | NQO2 (0.72) | NQO2WDR5F2 | |
| SCHEMBL3442777 | 0.63 | WDR5 (0.68) | NQO2WDR5F2PLGPRSS1 | |
| SCHEMBL9189037 | 0.63 | ITGB3 (0.54) | ITGB3ITGA2BALOX15 | |
| SCHEMBL7358257 | 0.63 | ITGB3 (0.71) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL11125777 | 0.63 | FABP4 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825994-A1 | AMIDINE DERIVATIVES USEFUL AS ANTI-PLATELET AGGREGATION INHIBITORS AND VASODILATORS | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5674894-A | Amidine derivatives useful as platelet aggregation inhibitors and vasodilators | G.D. SEARLE & CO. (US) | 1997-10-07 | — | — | US | disclosed |
| WO-1996036639-A1 | AMIDINE DERIVATIVES USEFUL AS ANTI-PLATELET AGGREGATION INHIBITORS AND VASODILATORS | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |