SCHEMBL11249006

SCHEMBL11249006

N#Cc1cn(-c2cc(Cl)cc(Cl)c2)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.57
KMT2A Q03164 5/20 0.56
MEN1 O00255 2/20 0.56
GAA P10253 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.40
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.36
DPYD Q12882 1/20 0.36
MCL1 Q07820 1/20 0.36
KDM4E B2RXH2 3/20 0.35
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11245813 0.86 L3MBTL1 (0.68) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11255394 0.85 L3MBTL1 (0.56) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11242715 0.84 L3MBTL1 (0.48) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11251532 0.82 GAA (0.50) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11239535 0.82 L3MBTL1 (0.46) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL8888929 0.82 L3MBTL1 (0.59) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL8888355 0.82 L3MBTL1 (0.55) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11255920 0.79 L3MBTL1 (0.80) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11253309 0.79 L3MBTL1 (0.49) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11248370 0.79 L3MBTL1 (0.67) L3MBTL1KMT2AMEN1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358591-A BACTERICIDES, FUNGICIDES; PLANT DISEASES ZOECON CORPORATION (US) 1982-11-09 US disclosed
US-4338318-A FUNGICIDE OR BACERICIDE TO TREAT PLANT DISEASES WITH A PHENYL URACIL ZOECON CORPORATION (US) 1982-07-06 US disclosed
US-4307098-A 2-PHENYL-URACIL COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-12-22 US disclosed
US-4297297-A α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates ZOECON CORP. (US) 1981-10-27 US disclosed
US-4266056-A FUNGICIDES, BACTERICIDES ZOECON CORPORATION (US) 1981-05-05 US disclosed