SCHEMBL2334036

SCHEMBL2334036

NC1(c2ccccc2)OC(=O)c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.61
GOPC Q9HD26 1/20 0.61
NPSR1 Q6W5P4 8/20 0.51
GAA P10253 2/20 0.51
POLB P06746 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
ATM Q13315 1/20 0.49
LMNA P02545 2/20 0.46
PKM P14618 1/20 0.46
CYP3A4 P08684 4/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 1/20 0.46
ESR1 P03372 1/20 0.46
TP53 P04637 1/20 0.46
TYMS P04818 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899522 0.96 CFTR (0.58) CFTRGOPCNPSR1GAAPOLB
SCHEMBL2334801 0.85 MAOA (0.56) CFTRGOPCNPSR1GAAPOLB
SCHEMBL11249029 0.77 CFTR (0.55) CFTRGOPCNPSR1GAAPOLB
SCHEMBL3886398 0.76 CFTR (1.00) CFTRGOPCNPSR1GAAPOLB
SCHEMBL17525320 0.76 CFTR (0.66) CFTRGOPCNPSR1GAAPOLB
SCHEMBL28445473 0.74 CFTR (0.58) CFTRGOPCNPSR1GAAPOLB
SCHEMBL9100605 0.73 CFTR (0.61) CFTRGOPCNPSR1GAAPOLB
SCHEMBL4726170 0.73 CFTR (0.61) CFTRGOPCNPSR1GAAPOLB
SCHEMBL28524472 0.73 CFTR (0.61) CFTRGOPCNPSR1GAAPOLB
SCHEMBL11932064 0.73 CFTR (0.61) CFTRGOPCNPSR1GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8501053-B2 Multi color, photoactive, color changing compositions and UV dosimeters BASF SE (DE) 2013-08-06 US disclosed
EP-2358840-B1 MULTI COLOR, PHOTOACTIVE, COLOR CHANGING COMPOSITIONS AND UV DOSIMETERS BASF SE (DE) 2012-12-26 EP disclosed
EP-2358840-A1 MULTI COLOR, PHOTOACTIVE, COLOR CHANGING COMPOSITIONS AND UV DOSIMETERS BASF SE (DE) 2011-08-24 EP disclosed
WO-2010037660-A1 MULTI COLOR, PHOTOACTIVE, COLOR CHANGING COMPOSITIONS AND UV DOSIMETERS BASF SE (DE) 2010-04-08 WO disclosed
EP-0279104-A1 Image producing material SEIKO INSTRUMENTS INC. (JP) 1988-08-24 EP disclosed