Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2828337 | 0.65 | POLB (0.44) | POLBGAAALDH1A1HTTLMNA | |
| SCHEMBL9326162 | 0.64 | HTT (0.39) | GAAALDH1A1HTTLMNANPC1 | |
| SCHEMBL14007388 | 0.63 | MGLL (0.49) | ALDH1A1MAPTSMN1; SMN2NPSR1HIF1A | |
| SCHEMBL11337998 | 0.63 | MGLL (0.45) | ALDH1A1HTTLMNACA9MGLL | |
| SCHEMBL13787110 | 0.63 | MGLL (0.45) | ALDH1A1HTTLMNACA9MGLL | |
| SCHEMBL14007602 | 0.62 | KDM4E (0.50) | POLBALDH1A1HTTLMNANPC1 | |
| SCHEMBL3488539 | 0.61 | HTT (0.41) | POLBGAAALDH1A1HTTNPC1 | |
| SCHEMBL21523338 | 0.60 | ALDH1A1 (0.51) | POLBGAAALDH1A1HTTLMNA | |
| SCHEMBL15954176 | 0.60 | POLB (0.47) | POLBGAAALDH1A1HTTLMNA | |
| SCHEMBL2511848 | 0.59 | POLB (0.60) | POLBGAAALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009095-B1 | 1.3.4-OXADIAZOLE-2-ONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-13 | — | — | EP | disclosed |
| EP-0009095-A1 | 1.3.4-Oxadiazole-2-one derivatives, processes for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-02 | — | — | EP | disclosed |