Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236624 | 0.82 | RAB9A (0.46) | KMT2AMAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11445418 | 0.80 | MAPT (0.69) | KMT2AMAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11239850 | 0.79 | CHRNB2 (0.42) | MAPTL3MBTL1ALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL6469206 | 0.76 | MAPT (0.62) | KMT2AMAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11226908 | 0.75 | TDP1 (0.53) | KMT2AMAPTALDH1A1TDP1RAB9A | |
| SCHEMBL5363442 | 0.75 | RAB9A (0.46) | KMT2AMAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL430707 | 0.74 | RAB9A (0.66) | KMT2AMAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL7670876 | 0.74 | RAB9A (0.51) | KMT2AMAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL27668932 | 0.74 | MAPT (0.57) | KMT2AMAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11213049 | 0.74 | RAB9A (0.47) | KMT2AMAPTALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310527-A | DISORDERS OF CAROIAC RHYTHM AND CORONARY HEART DISEASES AND HYDPERTENSION | CIBA-GEIGY CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |
| US-4140789-A | ADRENERGIC BLOCKING AGENTS, CARDIOTONIC, ANTIARRHYTHMIA, HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |