Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249170 | 0.82 | KMT2A (0.47) | RAB9APOLBRECQLNPC1ALDH1A1 | |
| SCHEMBL11226908 | 0.81 | TDP1 (0.53) | RAB9APOLBRECQLNPC1ALDH1A1 | |
| SCHEMBL430707 | 0.81 | RAB9A (0.66) | RAB9APOLBRECQLNPC1ALDH1A1 | |
| SCHEMBL7670876 | 0.80 | RAB9A (0.51) | RAB9APOLBRECQLNPC1ALDH1A1 | |
| SCHEMBL11213049 | 0.80 | RAB9A (0.47) | RAB9APOLBRECQLNPC1ALDH1A1 | |
| SCHEMBL21996988 | 0.79 | HTR1A (0.57) | RAB9APOLBRECQLNPC1ALDH1A1 | |
| SCHEMBL5363442 | 0.78 | RAB9A (0.46) | RAB9APOLBRECQLNPC1ALDH1A1 | |
| SCHEMBL9671707 | 0.78 | RAB9A (0.46) | RAB9APOLBRECQLNPC1ALDH1A1 | |
| SCHEMBL12006023 | 0.78 | RAB9A (0.46) | RAB9APOLBRECQLNPC1ALDH1A1 | |
| SCHEMBL6930910 | 0.77 | ALDH1A1 (0.62) | RAB9ARECQLNPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310527-A | DISORDERS OF CAROIAC RHYTHM AND CORONARY HEART DISEASES AND HYDPERTENSION | CIBA-GEIGY CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |
| US-4140789-A | ADRENERGIC BLOCKING AGENTS, CARDIOTONIC, ANTIARRHYTHMIA, HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |