Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ozone SCHEMBL11388736 | 0.96 | ALDH1A1 (0.36) | ALDH1A1CASP1SMN1; SMN2CYP2C19ABCB11 | |
| SCHEMBL11265307 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CASP1SMN1; SMN2CYP2C19ABCB11 | |
| SCHEMBL11393611 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CASP1SMN1; SMN2CYP2C19ABCB11 | |
| SCHEMBL11269399 | 0.86 | ALDH1A1 (0.33) | ALDH1A1OPRM1 | |
| SCHEMBL11387494 | 0.86 | ALDH1A1 (0.33) | ALDH1A1OPRM1 | |
| SCHEMBL11256342 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11390896 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11381243 | 0.84 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CYP2C19KMT2ACYP3A4 | |
| SCHEMBL11381249 | 0.84 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CYP2C19KMT2ACYP3A4 | |
| SCHEMBL11384161 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009560-A1 | 1,4-Dihydropyridazine-3-carbonyl compounds, process for their preparation, the compounds for use in curing diseases, medicaments containing them and process for the preparation of the medicaments | BAYER AG (DE) | 1980-04-16 | — | — | EP | claimed |
| EP-0009560-B1 | 1,4-DIHYDROPYRIDAZINE-3-CARBONYL COMPOUNDS, PROCESS FOR THEIR PREPARATION, THE COMPOUNDS FOR USE IN CURING DISEASES, MEDICAMENTS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF THE MEDICAMENTS | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |