Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxazafone SCHEMBL2108261 | 0.86 | GABRP (0.69) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Oxazafone SCHEMBL30090496 | 0.86 | GABRP (0.69) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11244823 | 0.85 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11147497 | 0.82 | ALDH1A1 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11248542 | 0.81 | ALDH1A1 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4703665 | 0.74 | MAPT (0.51) | C5AR1MAPTPOLBALDH1A1HTT | |
| SCHEMBL4707506 | 0.74 | MAPT (0.51) | C5AR1MAPTPOLBALDH1A1HTT | |
| SCHEMBL11050667 | 0.74 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11253143 | 0.73 | ALDH1A1 (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11143341 | 0.73 | ALDH1A1 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015214-B1 | DERIVATIVES OF SUBSTITUTED 2-BENZOYL GLYCINANILIDES, THEIR PREPARATION AND THEIR USE IN ANXIOLYTIC MEDICAMENTS | PIERRE FABRE S.A. (FR) | 1982-01-27 | — | — | EP | claimed |