Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11248207 | 0.90 | HTR2A (0.49) | HTR7HTR2AHRH1KDM4EALDH1A1 | |
| SCHEMBL11250946 | 0.81 | CHRM1 (0.36) | HTR7HTR2AHRH1KDM4EALDH1A1 | |
| SCHEMBL11488301 | 0.81 | HTR7 (0.47) | HTR7HTR2AHRH1KDM4EALDH1A1 | |
| SCHEMBL11334274 | 0.81 | CHRM1 (0.40) | KDM4EALDH1A1SMN1; SMN2ADRB2CHRM1 | |
| Hydrochloric Acid SCHEMBL11500011 | 0.80 | ALDH1A1 (0.36) | HTR7HTR2AHRH1KDM4EALDH1A1 | |
| SCHEMBL11334916 | 0.80 | ABCB1 (0.40) | HTR7HTR2AHRH1KDM4EALDH1A1 | |
| SCHEMBL11251898 | 0.80 | SCN1A (0.49) | KDM4EALDH1A1SMN1; SMN2CHRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL11256664 | 0.78 | ABCB1 (0.39) | HTR2AHRH1KDM4EALDH1A1ADRB2 | |
| SCHEMBL11250041 | 0.78 | ALDH1A1 (0.46) | HTR7HTR2AHRH1KDM4EALDH1A1 | |
| SCHEMBL11289438 | 0.77 | DPP4 (0.42) | HTR2AHRH1ALDH1A1CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015776-B1 | 1,1'-BIPHENYL-2-YL ALKYLAMINE DERIVATIVES, THEIR PRODUCTION AND CARDIOVASCULAR PREPARATIONS CONTAINING SAME | ELI LILLY AND COMPANY (US) | 1982-06-30 | — | — | EP | disclosed |
| US-4277471-A | 1,1-Biphenyl-2-yl alkylamines, formulations and antiarrhythmic treatment | ELI LILLY AND COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
| EP-0015776-A1 | 1,1'-Biphenyl-2-yl alkylamine derivatives, their production and cardiovascular preparations containing same | ELI LILLY AND COMPANY (US) | 1980-09-17 | — | — | EP | disclosed |