Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | FABP3 | P05413 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249537 | 1.00 | GABRA1 (0.53) | GABRA1GABRB2CA1CA2FABP3 | |
| SCHEMBL29617422 | 0.78 | GABRA1 (0.57) | GABRA1GABRB2CA1CA2FABP3 | |
| SCHEMBL3965396 | 0.78 | GABRA1 (0.57) | GABRA1GABRB2CA1CA2FABP3 | |
| SCHEMBL94533 | 0.76 | GABRA1 (0.77) | GABRA1GABRB2CA1CA2FABP3 | |
| Ammonia Solution, Strong SCHEMBL28098766 | 0.74 | GABRA1 (0.74) | GABRA1GABRB2CA1CA2FABP3 | |
| SCHEMBL11249541 | 0.72 | GABRA1 (0.50) | GABRA1GABRB2CA1CA2FABP3 | |
| SCHEMBL26521897 | 0.71 | GABRA1 (0.63) | GABRA1GABRB2CA1CA2FABP3 | |
| SCHEMBL15064751 | 0.70 | GABRA1 (0.68) | GABRA1GABRB2CA1CA2FABP3 | |
| SCHEMBL1617739 | 0.70 | GABRA1 (1.00) | GABRA1GABRB2CA1CA2FABP3 | |
| SCHEMBL8897499 | 0.69 | GABRA1 (0.61) | GABRA1GABRB2CA1CA2FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347288-A | High-voltage cable having a polythene containing insulation sheath which is provided with means to avoid or impede the formation or the growth of watertrees, the means comprising a metal complex | U.S. PHILIPS CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |
| EP-0027300-A1 | High-voltage cable having a polyethylene containing insulation sheath which is provided with means to avoid or impede the formation or the growth of watertrees | Koninklijke Philips Electronics N.V. (NL) | 1981-04-22 | — | — | EP | disclosed |