Tyramine

Tyramine

SCHEMBL11249547

NCCc1ccc(O)cc1.O=CCc1ccc(O)cc1

nearest known ligand 0.72

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 8/20 0.72
KDM4E B2RXH2 3/20 0.72
ADRA2A P08913 3/20 0.72
SLC6A2 P23975 3/20 0.72
ALDH1A1 P00352 2/20 0.72
HTR1A P08908 2/20 0.72
CYP2C19 P33261 1/20 0.72
HTR3A P46098 1/20 0.72
BACE1 P56817 1/20 0.72
L3MBTL1 Q9Y468 1/20 0.72
TDP1 Q9NUW8 3/20 0.69
BLM P54132 2/20 0.69
KMT2A Q03164 1/20 0.69
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
ABAT P80404 1/20 0.46
CA2 P00918 2/20 0.45
DRD2 P14416 3/20 0.44
DRD1 P21728 3/20 0.44
MAPT P10636 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13269343 0.89 TAAR1 (0.52) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL134515 0.85 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL30831130 0.85 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL30831107 0.85 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL4111 0.85 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
SCHEMBL105690 0.85 ESR1 (0.52) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL2190806 0.83 TAAR1 (0.78) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL1804993 0.83 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL3950268 0.83 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL7742928 0.83 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4353983-A ELECTROCHEMISTRY BATTELLE MEMORIAL INSTITUTE (CH) 1982-10-12 US disclosed
EP-0020623-A1 ANALYTICAL PROCESS AND MEANS FOR MEASURING THE AMOUNT OF HYDROGEN PEROXIDE IN AQUEOUS MEDIA AND OF ORGANIC SUBSTRATES GENERATING HYDROGEN PEROXIDE BY ENZYMATIC OXIDATION. BATTELLE MEMORIAL INSTITUTE (CH) 1981-01-07 EP disclosed
WO-1980001081-A1 ANALYTICAL PROCESS AND MEANS FOR MEASURING THE AMOUNT OF HYDROGEN PEROXIDE IN AQUEOUS MEDIA AND OF ORGANIC SUBSTRATES GENERATING HYDROGEN PEROXIDE BY ENZYMATIC OXIDATION BATTELLE MEMORIAL INSTITUTE (CH) 1980-05-29 WO disclosed