Tyramine

Tyramine

SCHEMBL30831107

[15NH2][13CH2][13CH2][13c]1[13cH][13cH][13c](O)[13cH][13cH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 9/20 1.00
KDM4E B2RXH2 3/20 1.00
ADRA2A P08913 3/20 1.00
SLC6A2 P23975 3/20 1.00
ALDH1A1 P00352 2/20 1.00
HTR1A P08908 2/20 1.00
CYP2C19 P33261 1/20 1.00
HTR3A P46098 1/20 1.00
BACE1 P56817 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
TDP1 Q9NUW8 3/20 0.95
BLM P54132 2/20 0.95
KMT2A Q03164 1/20 0.95
ESR1 P03372 2/20 0.68
ESR2 Q92731 2/20 0.68
ABAT P80404 1/20 0.62
CA2 P00918 1/20 0.59
HTR2A P28223 3/20 0.56
CYP2A6 P11509 2/20 0.56
CYP1A2 P05177 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyramine SCHEMBL30831130 1.00 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL134515 1.00 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL4111 1.00 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL31718804 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL32663617 0.97 TDP1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL7742928 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL31738431 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL3950268 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL2121 0.97 TDP1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL1804993 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250092060-A1 PHENOLIC COMPOUNDS SUBSTITUTED WITH NON-RADIOACTIVE ISOTOPES AND USES THEREOF SEQUL NATIONAL UNIVERSITY R&DB FOUNDATON (KR) 2025-03-20 US disclosed
WO-2024049154-A1 PHENOL COMPOUND SUBSTITUTED WITH NON-RADIOACTIVE ISOTOPE, AND USE THEREOF 서울대학교산학협력단 2024-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092060-A1 PHENOLIC COMPOUNDS SUBSTITUTED WITH NON-RADIOACTIVE ISOTOPES AND USES THEREOF APEX1, MCU, SLC25A1 TAAR1 4071/4885KDM4E 2197/4885ADRA2A 4353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.