Tyramine

Tyramine

SCHEMBL4111

NCCc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 9/20 1.00
KDM4E B2RXH2 3/20 1.00
ADRA2A P08913 3/20 1.00
SLC6A2 P23975 3/20 1.00
ALDH1A1 P00352 2/20 1.00
HTR1A P08908 2/20 1.00
CYP2C19 P33261 1/20 1.00
HTR3A P46098 1/20 1.00
BACE1 P56817 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
TDP1 Q9NUW8 3/20 0.95
BLM P54132 2/20 0.95
KMT2A Q03164 1/20 0.95
ESR1 P03372 2/20 0.68
ESR2 Q92731 2/20 0.68
ABAT P80404 1/20 0.62
CA2 P00918 1/20 0.59
HTR2A P28223 3/20 0.56
CYP2A6 P11509 2/20 0.56
CYP1A2 P05177 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyramine SCHEMBL30831130 1.00 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL134515 1.00 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL30831107 1.00 TAAR1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL31718804 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL32663617 0.97 TDP1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL7742928 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL31738431 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL3950268 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL2121 0.97 TDP1 (1.00) TAAR1KDM4EADRA2ASLC6A2ALDH1A1
Tyramine SCHEMBL1804993 0.97 TAAR1 (0.95) TAAR1KDM4EADRA2ASLC6A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 43704 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144732-A1 MELANIN HAIR DYE WITH THICKENERS NORTHWESTERN UNIVERSITY (US) 2026-05-28 US claimed
EP-3836899-B1 CHEMOTHERAPEUTIC PHARMACEUTICAL SUSPENSION FOR ORAL DOSAGE ONCOSOL LTD (GB) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122080927-A Biogenic amine visual detection method based on carbon dot/quantum dot ratio fluorescent probe and application 2026-05-26 CN claimed
CN-122075406-A Ensifen pharmaceutical composition, preparation method and application thereof 2026-05-26 CN claimed
CN-122081151-A Lactobacillus buchneri LW2 capable of reducing nitrite content and application thereof 2026-05-26 CN claimed
CN-122071606-A High-performance epoxy resin and preparation method thereof 大连理工大学 2026-05-22 CN claimed
WO-2026104471-A1 A SURGICAL MESH COATED WITH LIGHT-ACTIVATED ADHESIVE SOFRADIM PRODUCTION (FR) 2026-05-21 WO claimed
WO-2026106796-A1 SYSTEM AND METHOD FOR THE TREATMENT OF TELOGEN EFFLUVIUM, ANDROGENETIC ALOPECIA, AND OTHER HAIR LOSS DISORDERS FOLLEA INTERNATIONAL (US) 2026-05-21 WO claimed
CN-122063177-A Kit for detecting tumor cells based on electrochemical analysis and application thereof 上海大学 2026-05-19 CN claimed
US-4207308-A BY EXTRACTION AND CHROMATOGRAPHY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF VETERANS AFFAIRS (US) 1980-06-10 US claimed
US-4190593-A AMIDES OF 6-ALPHA-CARBOXYMETHYLTHIOCORTISOL DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) 1980-02-26 US claimed
EP-0000107-A1 Metallic or metallised article coated with a polyphenylene oxide film carrying reactive groups, its electrochemical preparation and its use ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1978-12-20 EP claimed
US-4128629-A IMMUNOASSAY CORNING GLASS WORKS (US) 1978-12-05 US claimed
US-4127423-A SODIUM SILICATE, SODIUM CHLORIDE, ETHYLENEDIAMINETETRAACETIC ACID, A CELLULOSE POLYVINYL ALCOHOL, NONIONIC SURFACTANT BURTON, PARSONS AND COMPANY, INC. (US) 1978-11-28 US claimed
US-4032406-A MEASURING OXYGEN-UPTAKE VIA HYDROXYLATION OF DOPAMINE OR TYRAMINE; ASCORBATE, FUMARATE MONSANTO COMPANY (US) 1977-06-28 US claimed
US-3997525-A Tetra-125 iodo-di-tyramine of digitalis derivative and process for making the same BIO-TEC, INC. (US) 1976-12-14 US claimed
US-3993436-A Dyeing live hair with melanin precursors SHISEIDO CO., LTD. (JA) 1976-11-23 US claimed
US-3933813-A Process for the production of mercaptoethyl containing compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-01-20 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed