Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189795 | 0.85 | MEN1 (0.50) | KMT2AMEN1PKMHPGDTSHR | |
| SCHEMBL6691255 | 0.80 | TOP2A (0.45) | KMT2AMEN1PKMALDH1A1HPGD | |
| SCHEMBL11107244 | 0.76 | TTR (0.50) | KMT2AMEN1PKMALDH1A1HPGD | |
| SCHEMBL11223180 | 0.76 | ALDH1A1 (0.42) | KMT2AMEN1PKMALDH1A1HPGD | |
| SCHEMBL10394363 | 0.75 | POLM (0.63) | KMT2AMEN1PKMALDH1A1HPGD | |
| SCHEMBL11223702 | 0.75 | ALDH1A1 (0.42) | KMT2AMEN1PKMALDH1A1TOP2A | |
| SCHEMBL11148733 | 0.74 | TOP2A (0.34) | KMT2AMEN1ALDH1A1HPGDTOP2A | |
| SCHEMBL4644681 | 0.73 | GAA (0.50) | KMT2AALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL28361567 | 0.73 | CES2 (0.41) | KMT2AALDH1A1CXCL8TOP2ASMN1; SMN2 | |
| SCHEMBL10784906 | 0.73 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366171-A | Fungicidal biphenyl esters, mixtures thereof and method of use | GAF CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |