Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691255 | 0.87 | TOP2A (0.45) | MEN1KMT2APKMHPGDHTT | |
| SCHEMBL8496813 | 0.86 | PTK2B (0.47) | MEN1KMT2APKMPTK2BCXCL8 | |
| SCHEMBL11249673 | 0.85 | KMT2A (0.40) | MEN1KMT2APKMCXCL8HPGD | |
| SCHEMBL6964590 | 0.85 | ALDH1A1 (0.44) | MEN1KMT2APKMPTK2BCXCL8 | |
| SCHEMBL27645038 | 0.84 | KMT2A (0.46) | MEN1KMT2APKMPTK2BCXCL8 | |
| SCHEMBL8498810 | 0.82 | KMT2A (0.50) | MEN1KMT2APKMPTK2BCXCL8 | |
| SCHEMBL578720 | 0.82 | ELANE (0.46) | MEN1KMT2APKMPTK2BCXCL8 | |
| SCHEMBL635048 | 0.82 | PTK2B (0.45) | MEN1KMT2APKMPTK2BCXCL8 | |
| SCHEMBL9799609 | 0.82 | ELANE (0.46) | MEN1KMT2APKMPTK2BCXCL8 | |
| SCHEMBL15442189 | 0.82 | PTK2B (0.45) | MEN1KMT2APKMPTK2BCXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434789-A | BTA analog derivative and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-12-05 | — | — | CN | disclosed |