Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.76 |
| ▸ | POLB | P06746 | 3/20 | 0.73 |
| ▸ | CASP6 | P55212 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | APAF1 | O14727 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | CASP7 | P55210 | 1/20 | 0.73 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stephanine SCHEMBL29543045 | 0.87 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Stephanine SCHEMBL25472587 | 0.87 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Stephanine SCHEMBL27780270 | 0.87 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Pukateine SCHEMBL30373684 | 0.85 | KDM4E (0.74) | DRD2POLBCASP6KMT2AMEN1 | |
| Pukateine SCHEMBL674930 | 0.85 | KDM4E (0.74) | DRD2POLBCASP6KMT2AMEN1 | |
| Roemerine SCHEMBL678048 | 0.85 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Roemerine SCHEMBL673805 | 0.85 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Roemerine SCHEMBL30047645 | 0.85 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Roemerine SCHEMBL30047807 | 0.85 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Roemerine SCHEMBL17906539 | 0.85 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309542-A | WITH A TRIMETHYLPHENYLAMMONIUM BASE | WARNER-LAMBERT COMPANY (US) | 1982-01-05 | — | — | US | disclosed |