Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | CASP6 | P55212 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | APAF1 | O14727 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | CASP7 | P55210 | 1/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 1/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 1/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 0.73 |
| ▸ | ACHE | P22303 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Roemerine SCHEMBL30047645 | 1.00 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Roemerine SCHEMBL30047807 | 1.00 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Roemerine SCHEMBL673805 | 1.00 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Roemerine SCHEMBL17906539 | 1.00 | DRD2 (1.00) | DRD2POLBCASP6KMT2AMEN1 | |
| Neolitsine SCHEMBL31029789 | 0.88 | POLB (0.81) | DRD2POLBCASP6KMT2AMEN1 | |
| SCHEMBL10941634 | 0.86 | DRD2 (0.76) | DRD2POLBCASP6KMT2AMEN1 | |
| SCHEMBL10750734 | 0.86 | DRD2 (0.76) | DRD2POLBCASP6KMT2AMEN1 | |
| SCHEMBL11249155 | 0.85 | DRD2 (0.74) | DRD2POLBCASP6KMT2AMEN1 | |
| SCHEMBL11249690 | 0.85 | DRD2 (0.76) | DRD2POLBCASP6KMT2AMEN1 | |
| Isolaureline SCHEMBL29761843 | 0.85 | BCHE (1.00) | DRD2POLBCASP6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257887-A2 | Ophthalmic compositions | HOUSTON BIOTECHNOLOGY INCORPORATED (US) | 1988-03-02 | — | — | EP | claimed |
| US-20130023487-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2013-01-24 | — | — | US | disclosed |
| US-20130023487-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2013-01-24 | — | — | US | disclosed |
| US-20120190734-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2012-07-26 | — | — | US | disclosed |
| US-20120190734-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2012-07-26 | — | — | US | disclosed |
| US-8067401-B2 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2011-11-29 | — | — | US | disclosed |
| US-8067401-B2 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2011-11-29 | — | — | US | disclosed |
| US-20090069277-A1 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LTD. | 2009-03-12 | — | — | US | disclosed |
| US-20090069277-A1 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LTD. | 2009-03-12 | — | — | US | disclosed |
| EP-0257887-A2 | Ophthalmic compositions | HOUSTON BIOTECHNOLOGY INCORPORATED (US) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190734-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | RPN2, LSS, CLIC4 | DRD2 252/4885POLB 1879/4885CASP6 508/4885 |
| US-20130023487-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | RPN2, LSS, CLIC4 | DRD2 252/4885POLB 1879/4885CASP6 508/4885 |
| US-20090069277-A1 | Compounds and compositions for treating infection | RPN2, LSS, CLIC4 | DRD2 252/4885POLB 1879/4885CASP6 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.