Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625410 | 0.74 | — | — | |
| SCHEMBL28433643 | 0.73 | LTA4H (0.50) | LTA4HTSHRCA4KCNA3CA5A | |
| Hydrochloric Acid SCHEMBL1074228 | 0.71 | LTA4H (0.47) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL29524653 | 0.69 | — | — | |
| SCHEMBL16517020 | 0.63 | LTA4H (0.37) | LTA4HTSHRCA4ALDH1A1L3MBTL1 | |
| SCHEMBL28649614 | 0.63 | — | — | |
| SCHEMBL25360523 | 0.61 | ALDH1A1 (0.40) | LTA4HTSHRCA4CA1CA2 | |
| SCHEMBL218376 | 0.61 | ALDH1A1 (0.40) | LTA4HTSHRCA4CA1CA2 | |
| SCHEMBL14905 | 0.61 | LTA4H (0.60) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL1649854 | 0.61 | ALDH1A1 (0.40) | LTA4HTSHRCA4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101319090-B | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | ROHM & HAAS | 2012-07-18 | — | — | CN | disclosed |
| CN-101528213-B | Combination of modafinil and an antagonist or inverse agonist of the h3 receptor | BIOPROJET (FR) | 2012-02-15 | — | — | CN | disclosed |
| CN-101528213-A | Combination of modafinil and an antagonist or inverse agonist of the H3 receptor | BIOPROJET SOC CIV (FR) | 2009-09-09 | — | — | CN | disclosed |
| CN-101319090-A | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | ROHM & HAAS (US) | 2008-12-10 | — | — | CN | disclosed |
| CN-1034203-A | The tetrazolinone that Phenoxyphenyl replaces | UNIROYAL CHEM CO INC (US) | 1989-07-26 | — | — | CN | disclosed |
| EP-0064344-A1 | Silicate binder compositions used in single package zinc and ceramics coating compositions and a method of curing silicate binder compositions | MOBIL OIL CORPORATION (US) | 1982-11-10 | — | — | EP | disclosed |