SCHEMBL28433643

SCHEMBL28433643

c1ccc(O[Sn]Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.50
TSHR P16473 1/20 0.50
CA4 P22748 1/20 0.45
KCNA3 P22001 1/20 0.41
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
MAOA P21397 1/20 0.38
DRD4 P21917 2/20 0.37
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
ALDH1A1 P00352 1/20 0.36
RECQL P46063 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
SRC P12931 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1074228 0.97 LTA4H (0.47) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL29524653 0.75
SCHEMBL11249932 0.73 LTA4H (0.43) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL106233 0.69
SCHEMBL28649614 0.69
Diphenylether SCHEMBL9061108 0.67 LTA4H (1.00) LTA4HTSHRCA4NR1H2BAX
Diphenylether SCHEMBL4950525 0.67 LTA4H (1.00) LTA4HTSHRCA4NR1H2BAX
SCHEMBL14905 0.67 LTA4H (0.60) LTA4HTSHRCA4KCNA3CA5A
Diphenylether SCHEMBL2461810 0.67 LTA4H (1.00) LTA4HTSHRCA4NR1H2BAX
Diphenylether SCHEMBL12286 0.67 LTA4H (1.00) LTA4HTSHRCA4NR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115651604-A Low-odor coated dealcoholized transparent flowing sealant for electronic and electric appliances 上海清臣环保科技有限公司 2023-01-31 CN claimed
CN-108882704-B Molecules having pesticidal utility, and intermediates, compositions and methods related to these molecules 美国陶氏益农公司 2021-09-10 CN claimed
CN-115651604-A Low-odor coated dealcoholized transparent flowing sealant for electronic and electric appliances 上海清臣环保科技有限公司 2023-01-31 CN disclosed
CN-115551522-A Cellular immunotherapy for the treatment of cancer 得克萨斯大学体系董事会 2022-12-30 CN disclosed
CN-115279382-A Compositions and methods for delivering bacterial metabolites to a subject 芬奇治疗控股有限责任公司 2022-11-01 CN disclosed
CN-115243728-A Method for engineering natural killer cells to target CD70 positive tumors 得克萨斯大学体系董事会 2022-10-25 CN disclosed
CN-109641066-B Novel IgG-binding peptides and multifunctional antigen-binding proteins containing the same 宾夕法尼亚大学理事会 2022-06-21 CN disclosed
CN-114026060-A Acrylate derivative, use thereof, and intermediate for production thereof 住友化学株式会社 2022-02-08 CN disclosed
CN-111328331-A Compositions and methods for decolonizing antibiotic-resistant bacteria in the intestinal tract 芬奇治疗公司 2020-06-23 CN disclosed
CN-111328284-A Compositions and methods for maintaining and restoring a healthy intestinal barrier 芬奇治疗公司 2020-06-23 CN disclosed