Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19809897 | 1.00 | EPHX1 (0.38) | EPHX1GABRR1GRM2GRM3SLC1A2 | |
| SCHEMBL19809803 | 0.82 | EPHX1 (0.53) | EPHX1 | |
| SCHEMBL19809890 | 0.79 | TRPM8 (0.36) | EPHX1CYP2C19TRPM8 | |
| SCHEMBL24072311 | 0.78 | GABRR1 (0.42) | EPHX1GABRR1GRM2GRM3SLC1A2 | |
| SCHEMBL12808697 | 0.78 | GABRR1 (0.42) | EPHX1GABRR1GRM2GRM3SLC1A2 | |
| SCHEMBL19730178 | 0.78 | GABRR1 (0.42) | EPHX1GABRR1GRM2GRM3SLC1A2 | |
| SCHEMBL8286216 | 0.75 | GABRR1 (0.48) | GABRR1GRM2GRM3SLC1A2CYP2C9 | |
| SCHEMBL8175844 | 0.75 | GABRR1 (0.48) | GABRR1GRM2GRM3SLC1A2CYP2C9 | |
| SCHEMBL11250069 | 0.72 | EPHX1 (0.33) | EPHX1GABRR1GRM2GRM3MEN1 | |
| SCHEMBL11000712 | 0.72 | PPP5C (0.39) | GABRR1GRM2GRM3CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696884-B2 | Compositions comprising menthol compounds as smoothing agents | SYMRISE AG (DE) | 2023-07-11 | — | — | US | disclosed |
| US-20180042832-A1 | COMPOSITIONS COMPRISING MENTHOL COMPOUNDS AS SMOOTHING AGENTS | SYMRISE AG (DE) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696884-B2 | Compositions comprising menthol compounds as smoothing agents | SMURF1, SMURF2, S1PR2 | EPHX1 2359/4885GABRR1 61/4885GRM2 958/4885 |
| US-20180042832-A1 | COMPOSITIONS COMPRISING MENTHOL COMPOUNDS AS SMOOTHING AGENTS | SMURF1, SMURF2, S1PR2 | EPHX1 2359/4885GABRR1 61/4885GRM2 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.