Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9941454 | 0.81 | TYR (0.42) | KMT2AMEN1IDO1TDO2MAPT | |
| SCHEMBL21420998 | 0.77 | IDO1 (0.41) | KMT2AIDO1TDO2ALDH1A1GAA | |
| SCHEMBL8060858 | 0.76 | GABRA1 (0.45) | KMT2AMEN1CYP2C9ALDH1A1SLC6A2 | |
| SCHEMBL3039320 | 0.75 | IDO1 (0.58) | KMT2AMEN1IDO1TDO2MAPT | |
| SCHEMBL703095 | 0.74 | IDO1 (0.39) | KMT2AMEN1IDO1TDO2MAPT | |
| SCHEMBL18011789 | 0.74 | IDO1 (0.39) | KMT2AMEN1IDO1TDO2MAPT | |
| SCHEMBL2571438 | 0.73 | CA2 (0.38) | KMT2AIDO1MAPTALDH1A1GAA | |
| SCHEMBL6241172 | 0.73 | DRD2 (0.41) | KMT2AMEN1IDO1TDO2MAPT | |
| SCHEMBL28120983 | 0.72 | KMT2A (0.42) | KMT2AMEN1IDO1TDO2MAPT | |
| SCHEMBL3261670 | 0.71 | IDO1 (0.58) | KMT2AMEN1IDO1TDO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342875-A | STABILIZERS FOR OLEFIN POLYMERS | CINCINNATI-MILACRON, INC. (US) | 1982-08-03 | — | — | US | disclosed |
| US-4012399-A | ULTRAVIOLET LIGHT ABSORBERS AND STABILIZERS | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1977-03-15 | — | — | US | disclosed |
| US-4000101-A | POLYPROPYLENE | WESTON CHEMICAL CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3959220-A | Polymer additives comprising transition metal complexes with trivalent phosphorous compounds | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1976-05-25 | — | — | US | disclosed |