SCHEMBL11250285

SCHEMBL11250285

C(=C/c1ccc2[nH]c3ccc(/C=C/c4ccccc4)cc3c2c1)\c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.56
RELA Q04206 1/20 0.50
IP6K1 Q92551 2/20 0.49
IP6K3 Q96PC2 1/20 0.46
IP6K2 Q9UHH9 1/20 0.46
MAOA P21397 4/20 0.45
MAOB P27338 4/20 0.45
NFE2L2 Q16236 2/20 0.45
CYP19A1 P11511 2/20 0.45
AHR P35869 1/20 0.45
CYP1A1 P04798 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP1B1 Q16678 1/20 0.44
ALK Q9UM73 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
GLA P06280 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11250289 1.00 KIF11 (0.56) KIF11RELAIP6K1IP6K3IP6K2
SCHEMBL28217117 0.94 KIF11 (0.66) KIF11RELAIP6K1IP6K3IP6K2
SCHEMBL13675832 0.82 NFE2L2 (0.50) KIF11RELANFE2L2KDM4EMEN1
(Z)-1,2-Diphenylethene SCHEMBL27647970 0.80 ALDH1A1 (0.67) KIF11MAOAMAOBAHRCYP1A2
(Z)-1,2-Diphenylethene SCHEMBL4393598 0.80 ALDH1A1 (0.67) KIF11MAOAMAOBAHRCYP1A2
(Z)-1,2-Diphenylethene SCHEMBL4393600 0.80 ALDH1A1 (0.67) KIF11MAOAMAOBAHRCYP1A2
SCHEMBL3270902 0.80 IP6K1 (0.50) KIF11IP6K1CYP1A1CYP1A2CYP1B1
SCHEMBL3270896 0.80 IP6K1 (0.50) KIF11IP6K1CYP1A1CYP1A2CYP1B1
SCHEMBL676476 0.79 IP6K1 (0.44) KIF11RELAIP6K1IP6K3IP6K2
SCHEMBL8079075 0.79 KIF11 (0.66) KIF11AHRKDM4EMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56032458-A None JP disclosed
JP-57165841-A None JP disclosed
CN-106488965-A Luminophor for luminescent device 日东电工株式会社 2017-03-08 CN disclosed
US-20160126478-A1 EMISSIVE COMPOUNDS FOR LIGHT EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2016-05-05 US disclosed
US-20160126478-A1 EMISSIVE COMPOUNDS FOR LIGHT EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2016-05-05 US disclosed
US-20160126478-A1 EMISSIVE COMPOUNDS FOR LIGHT EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2016-05-05 US disclosed
JP-S57165841-A ELECTROPHOTOGRAPHIC RECEPTOR ASAHI GLASS CO LTD 1982-10-13 JP disclosed
JP-S5632458-A 3,6-DISTYRYLCARBAZOLE DERIVATIVE AND ITS PREPARATION ASAHI GLASS CO LTD 1981-04-01 JP disclosed