Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253466 | 0.83 | RORC (0.48) | CSNK2A1RORCMEN1KMT2ALMNA | |
| SCHEMBL11259695 | 0.74 | TSHR (0.55) | KMT2ALMNACYP2C9CYP3A4HPGD | |
| SCHEMBL11259916 | 0.71 | TSHR (0.42) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL11263956 | 0.70 | TSHR (0.46) | LMNACYP3A4HSP90AA1S1PR1 | |
| SCHEMBL11253602 | 0.68 | ALDH1A1 (0.40) | MEN1KMT2ASMN1; SMN2NPSR1GLA | |
| SCHEMBL11619346 | 0.68 | RORC (0.45) | CSNK2A1RORCMEN1KMT2ALMNA | |
| SCHEMBL11775976 | 0.68 | CSNK2A1 (0.49) | CSNK2A1RORCMEN1KMT2ALMNA | |
| SCHEMBL27864755 | 0.66 | IRAK4 (0.41) | CSNK2A1RORCLMNASMN1; SMN2RXRA | |
| SCHEMBL2104888 | 0.66 | RORC (0.55) | CSNK2A1RORCMEN1KMT2ALMNA | |
| SCHEMBL2104049 | 0.65 | RORC (0.55) | CSNK2A1RORCMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358611-A | FROM A PHENYLHYDRAZINE, A CHLOROFORMATE, PHOSGENE AND A SECONDARY AMINE | SHELL OIL COMPANY (US) | 1982-11-09 | — | — | US | disclosed |