Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251111 | 0.89 | GRIK1 (0.53) | GRIK1GRIK2PPARAPPARGALDH1A1 | |
| SCHEMBL11259021 | 0.86 | PPARA (0.42) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11250422 | 0.82 | GRIK1 (0.50) | GRIK1GRIK2PPARAPPARGALDH1A1 | |
| SCHEMBL11255001 | 0.80 | GRIK2 (0.52) | GRIK1GRIK2PPARAABCB11CYP1A2 | |
| SCHEMBL11263777 | 0.79 | PPARA (0.44) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11257688 | 0.79 | PPARA (0.42) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11259004 | 0.79 | FBP1 (0.46) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL14136817 | 0.77 | GRIK2 (0.80) | GRIK1GRIK2TSHRALDH1A1MTNR1A | |
| SCHEMBL14062053 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL11290711 | 0.75 | PPARA (0.47) | PPARAABCB11CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |