Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251111 | 0.88 | GRIK1 (0.53) | GRIK1GRIK2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL11250419 | 0.82 | GRIK1 (0.49) | GRIK1GRIK2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL14136817 | 0.78 | GRIK2 (0.80) | GRIK1GRIK2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL14062053 | 0.77 | GRIK1 (0.55) | GRIK1GRIK2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL11258892 | 0.72 | ALDH1A1 (0.51) | GRIK1GRIK2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL8935937 | 0.72 | PPARG (0.53) | ALDH1A1L3MBTL1PPARGPPARA | |
| SCHEMBL82055 | 0.72 | PPARG (0.53) | ALDH1A1L3MBTL1PPARGPPARA | |
| SCHEMBL11688432 | 0.71 | GRIK1 (0.52) | GRIK1GRIK2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL11660383 | 0.70 | ALDH1A1 (0.65) | GRIK1GRIK2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL976929 | 0.70 | PTGER4 (0.53) | GRIK1GRIK2ALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |