Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257688 | 0.83 | PPARA (0.42) | FBP1PPARAPPARGABCB11CYP1A2 | |
| SCHEMBL11256556 | 0.81 | FBP1 (0.45) | FBP1PPARAPPARGABCB11CYP1A2 | |
| SCHEMBL11250419 | 0.79 | GRIK1 (0.49) | FBP1PPARAPPARGABCB11CYP1A2 | |
| SCHEMBL3824943 | 0.77 | FBP1 (0.66) | FBP1PPARAPPARGABCB11CYP1A2 | |
| SCHEMBL11251055 | 0.77 | ESR1 (0.44) | ALDH1A1RAB9AKMT2ACA9 | |
| SCHEMBL11259021 | 0.76 | PPARA (0.42) | FBP1PPARAPPARGABCB11CYP1A2 | |
| SCHEMBL11257361 | 0.72 | MTNR1A (0.45) | PPARAPPARGCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL654010 | 0.71 | FBP1 (0.65) | FBP1PPARAPPARGABCB11CYP1A2 | |
| SCHEMBL1972122 | 0.71 | BCL9 (0.51) | FBP1PPARAPPARGABCB11CYP1A2 | |
| SCHEMBL2884727 | 0.69 | NR1H2 (0.54) | SMN1; SMN2KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |